Follow the A28 or N33 and take the exit Assen-Zuid (exit 32). From there the circuit is well signed-out (see map below).
By public traffic
You can also visit the circuit by train. At the trainstation Assen there are special busses waiting. These busses bring the spectators of the race from the station to the circuit and back. You can use this special service from 8:45 to 11:05 in the morning and from 16:00 to 18.20 in the evening. You can buy tickets in the bus itself, the costs are 3 euro for a return ticket.